Physiologically relevant human iPSC-derived cell models and specialist services

Human iPSC-derived models

Cell provision and specialist services

• Predictive, highly validated disease and safety models
• Scalable differentiation and manufacture of cryopreserved iPSC-derived cells, shipped globally
• Comprehensive discovery and preclinical specialist services, including small molecule, ASO and AAV testing
• Model development, pilot and assay development expertise, including complex co-culture systems
• iPSC production and quality control, reprogramming and gene editing

Extensive patient and unaffected donor iPSC line portfolio

• Library of >100 iPSC lines from unaffected and patient donors representing over twenty indications with particular focus on neurodegenerative disorders and ophthalmology
• Collaboration with patient advocacy groups and PRISM ALS consortia
• Extensive quality control documentation and full commercial use ethical consents

Supporting NAMs (New Approach Methodologies)

• iPSC-derived cells validated on multiple MPS and advanced in vitro analysis platforms
• Support for tech transfer to CROs and in-house facilities