Digital Library

Access our comprehensive collection of research resources, application notes, and product documentation.

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  • Brochures

Physiologically relevant human iPSC-derived cell models and specialist services

Physiologically relevant human iPSC-derived cell models and specialist services for drug discovery and translational research At Axol Bioscience, we provide...

  • Application Notes

Physiologically relevant iPSC-derived retinal models for ophthalmology research & drug discovery

Our new whitepaper describes how human iPSC‑derived retinal models enable mechanistic studies, toxicity assessment, and improved translational relevance in ophthalmology...

  • Posters

Modeling ALS with iPSC-derived motor neurons

Learn how iPSC-derived motor neurons and triculture systems provide a robust, physiologically relevant platform for assessing ALS phenotypes and compound...

  • Posters

A contractility platform for engineered 3D muscle tissues

Explore our work in collaboration with Optics11 Life, showcasing our axoCells ventricular cardiomyocytes.

...
  • Posters

Human iPSC-derived motor neurons for ALS modeling on the high-throughput Nanion SyncroPatch 384 platform

Axol Bioscience has generated motor neurons from a number of patient and unaffected donor samples. We have previously reported ALS...

  • Brochures

iPSC Technology for Huntington’s disease eBook

Axol Bioscience provides a complete solution for Huntington’s disease research, offering iPSC-derived striatal neurons derived from patient and control iPSC...

  • Brochures

Functional motor neurons from patient iPSC lines to support ALS research and drug discovery

Axol Bioscience’s axoCells™ ALS Toolbox features iPSC-derived motor neurons from ALS patients and controls. This resource enables high-throughput, human-relevant in...

  • Application Notes

Modeling the genomic instability of Huntington’s Disease with iPSC technology

Axol Bioscience’s iPSC-derived striatal neurons model Huntington’s disease with CAG repeat instability and early-onset phenotypes. This study, we outline the...

  • Brochures

Chamber-specific human iPSC-derived cardiomyocytes for disease modeling and safety

MyoMax™ Maturation Media enhances the maturity of human iPSC-derived cardiomyocytes, improving morphology, electrophysiology, and metabolic function for more predictive in...

  • Brochures

Axol Bioscience – iPSCs and New Approach Methodologies (NAMs)

Explore Axol Bioscience’s 2025 Technology Journal showcasing how human iPSC-derived cells power advanced microphysiological systems (MPS) for drug discovery. Featuring...

  • Brochures

Physiologically relevant in vitro retinal models for ophthalmology drug discovery and safety testing

Our new ebook outlines key in vitro systems for retinal disease modeling and toxicology assessment using human iPSC‑derived cells.

...
  • Brochures

Cosmetics and Dermatology eBook

Explore Axol Bioscience’s iPSC-derived skin models for cosmetics and dermatology research. This eBook highlights sebocytes, melanocytes, and sensory neurons for...

  • Brochures

A new set of sporadic Alzheimer’s disease iPSCs to support pre-clinical in vitro model building and drug discovery

Discover Axol Bioscience’ and StrataStem’s new panel of iPSC lines from sporadic Alzheimer’s Disease (sAD) patients. This resource supports custom...

  • Posters

Tessara Therapeutics – Alzheimer’s Disease Organoids

Discover Axol Bioscience’s iPSC-derived neural stem cells powering Tessara Therapeutics’ RealBrain® 3D Alzheimer’s disease organoids. This poster highlights advanced neurodegenerative...

  • Posters

Sygnature Discovery – High content iPSC-derived microglia inflammatory model

Explore Axol Bioscience’s iPSC-derived microglia used in high-content imaging assays for neuroinflammation research. This poster highlights phagocytosis of Aβ1-42, TREM2...

  • Posters

Sygnature Discovery – Automation of iPSC workflows

Discover Axol Bioscience’s iPSC-derived microglia integrated into semi-automated workflows for scalable neuroinflammation research. This poster highlights automation platforms, liquid handling,...

  • Posters

Huntington’s Disease iPSCs-derived striatal neurons with 140 CAG repeats over a 100 day-culture

Explore Axol Bioscience’s iPSC-derived striatal neurons from Huntington’s disease patients with >140 CAG repeats. This poster highlights long-term culture, somatic...

  • Posters

Differential Responses of Chamber-Specific Human iPSC-Derived Cardiomyocytes for In Vitro Cardiotoxicity Studies

Explore Axol Bioscience’s chamber-specific iPSC-derived cardiomyocytes for cardiotoxicity screening. This poster highlights atrial, ventricular, and left ventricular models, metabolic maturation...

  • Posters

iPSC motor neuron NMJ models for enhancing breakthroughs in ALS

Explore Axol Bioscience’s iPSC-derived neuromuscular junction (NMJ) models for ALS research. This poster highlights motor neurons and skeletal muscle cells...

  • Posters

Human iPSC-Derived Cardiomyocytes for High Throughput In Vitro Cardiac Pharmacology and Cardiotoxicity Studies

Explore Axol Bioscience’s ventricular iPSC-derived cardiomyocytes for high-throughput cardiac pharmacology and cardiotoxicity testing. This poster highlights electrophysiological profiling on QPatch...

  • Application Notes

Sartorius – iPSC-Derived Motor Neurons and Microglia From ALS Background Display Disease Phenotype

Explore Axol Bioscience’s iPSC-derived motor neurons and microglia from ALS patients for disease modeling and drug discovery. This whitepaper highlights...

  • Application Notes

Analysis of axoCells atrial and ventricular cardiomyocytes electrophysiology using CorePlate enabled HD-MEA System

Explore Axol Bioscience’s atrial and ventricular iPSC-derived cardiomyocytes analyzed using 3Brain’s HD-MEA CorePlate system. This application note highlights spontaneous beating,...

  • Posters

Establishment of a Quality-Driven Manufacturing Process to Reprogram Human Donor Material into Human Induced Pluripotent Stem Cells (iPSCs) to Support Drug Discovery

Discover Axol Bioscience’s ISO 9001-accredited process for generating high-quality iPSCs from patient and healthy donors. This poster outlines ethical sourcing,...

  • Posters

Differentiation of Multiple iPSC Lines to Different Cell Types to Enable Cohort Analysis in Neurodegeneration: Challenges and Learnings

Explore Axol Bioscience’s cohort-level iPSC differentiation strategy for neurodegeneration research. This poster highlights the generation of astrocytes, cortical excitatory neurons,...

  • Posters

Creation of RUES2 Cell Lines Carrying Targeted Modifications at the HTT Gene

Explore Axol Bioscience’s CRISPR-engineered RUES2 hESC lines with targeted HTT gene modifications for Huntington’s disease research. This poster highlights CAG...

  • Posters

Characterization of Striatal Neurons Derived from >140 CAG iPSCs for Huntington’s Disease Modeling

Explore Axol Bioscience’s iPSC-derived striatal neurons from a Huntington’s disease patient with >140 CAG repeats. This poster highlights somatic instability,...

  • Posters

The Multiplatform Utility of Human iPSC-Derived Neuronal Models to Provide Complex Biological In Vitro Systems for Drug Discovery

Explore Axol Bioscience’s human iPSC-derived neuronal models across 2D and 3D microphysiological systems (MPS). This poster highlights motor and sensory...

  • Posters

innoVitro – Contractility-Based Pharmacological Characterization of hiPSC-Derived Atrial and Ventricular Cardiomyocytes for Preclinical Toxicity Testing

Explore Axol Bioscience’s chamber-specific iPSC-derived cardiomyocytes for contractility-based drug screening. This poster highlights FLEXcyte 96 technology, beat shape analysis, and...

  • Posters

Evaluation of a New Media Designed to Drive Improved Maturity of iPSC-Derived Cardiomyocytes for Cardiac Disease, Cardiotoxicity and Drug Screening

Explore Axol Bioscience’s cardiac maturation media for enhancing the functional maturity of iPSC-derived cardiomyocytes. This poster highlights improvements in sarcomere...

  • Posters

Harnessing the Potential of Induced Pluripotent Stem Cells to Accelerate Drug Discovery for Age-Related Macular Degeneration

Explore Axol Bioscience’s iPSC-derived RPE model for dry AMD research. This poster highlights A2E and blue light-induced stress, genetic risk...

  • Posters

Characterization of Human iPSC-Derived Motor Neuron Disease Model for ALS Drug Discovery

Explore Axol Bioscience’s iPSC-derived motor neuron model for ALS drug discovery. This poster highlights hyperexcitability, loss of synchronous firing, and...

  • Application Notes

Multielectrode array characterization of human iPSC-derived motor neuron disease model for ALS drug discovery

Explore Axol Bioscience’s iPSC-derived motor neuron model for ALS drug discovery. This application note highlights hyperexcitability, mutation-specific phenotypes, and reproducible...

  • Posters

Functional and Pharmacological Differences Between the Contractility of axoCells™ iPSC-Derived Atrial and Ventricular Cardiomyocytes Assessed on the FLEXcyte 96

Explore Axol Bioscience’s chamber-specific iPSC-derived cardiomyocytes for contractility-based drug screening. This poster highlights beat rate, waveform shape, and pharmacological responses...

  • Posters

Cross-Platform Validation of axoCells™ hiPSC-Derived Cardiomyocytes as a Better Human Model for Preclinical Cardiotoxicity Studies

Explore Axol Bioscience’s ventricular iPSC-derived cardiomyocytes validated across MEA, FLEXcyte 96, and CellOPTIQ platforms. This poster highlights chamber-specific pharmacology, marker...

  • Posters

Building a Functionally Relevant In Vitro Model of Alzheimer’s Disease with Patient-Derived iPSCs

Explore Axol Bioscience’s iPSC-derived Alzheimer’s disease model using patient lines with APOE4 and PSEN1 mutations. This poster highlights differentiation into...

  • Posters

Characterization of axoCells™ iPSC-Derived Cortical Inhibitory Interneurons

Explore Axol Bioscience’s iPSC-derived cortical inhibitory interneurons for neuroscience research. This poster highlights marker expression, electrophysiological profiling, and co-culture functionality...

  • Posters

Validation of a Cortical Tri-Culture Model for In Vitro Compound Screening: A Blinded Compound Study

Explore Axol Bioscience’s tri-culture model of cortical neurons, interneurons, and astrocytes for neurotoxicity and drug screening. This poster highlights MEA-based...

  • Posters

Utilizing Flow Cytometry Within a Quality Control Process for an iPSC-Based Manufacturing Facility

Explore Axol Bioscience’s use of flow cytometry for quality control in iPSC-based manufacturing. This poster highlights marker-based pass/fail thresholds for...

  • Posters

Establishing a Robust Platform for Investigating the Pro- and Anti-Inflammatory Response of iPSC-Derived Microglia in Drug Discovery

Explore Axol Bioscience’s iPSC-derived microglia platform for neuroinflammation research and drug screening. This study demonstrates reproducible cytokine release, transcriptomic and...

  • Application Notes

Functional and Pharmacological Differences Between the Contractility of axoCells™ iPSC-Derived Atrial and Ventricular Cardiomyocytes Assessed on the FLEXcyte 96

Axol Bioscience’s axoCells™ atrial and ventricular iPSC-derived cardiomyocytes reveal distinct contractility and drug responses on the FLEXcyte 96 platform. This...

  • Application Notes

axoCells™ ventricular cardiomyocytes as functionally-relevant cardiotoxicity models – external validation against CiPA compound panel

Axol Bioscience’s axoCells™ ventricular iPSC-derived cardiomyocytes were externally validated against the CiPA compound panel for cardiotoxicity screening. This study highlights...

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