Digital Library

Access our comprehensive collection of research resources, application notes, and product documentation.

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  • Posters

Modeling ALS with iPSC-derived motor neurons

Learn how iPSC-derived motor neurons and triculture systems provide a robust, physiologically relevant platform for assessing ALS phenotypes and compound...

  • Posters

A contractility platform for engineered 3D muscle tissues

Explore our work in collaboration with Optics11 Life, showcasing our axoCells ventricular cardiomyocytes.

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  • Posters

Human iPSC-derived motor neurons for ALS modeling on the high-throughput Nanion SyncroPatch 384 platform

Axol Bioscience has generated motor neurons from a number of patient and unaffected donor samples. We have previously reported ALS...

  • Posters

Tessara Therapeutics – Alzheimer’s Disease Organoids

Discover Axol Bioscience’s iPSC-derived neural stem cells powering Tessara Therapeutics’ RealBrain® 3D Alzheimer’s disease organoids. This poster highlights advanced neurodegenerative...

  • Posters

Sygnature Discovery – High content iPSC-derived microglia inflammatory model

Explore Axol Bioscience’s iPSC-derived microglia used in high-content imaging assays for neuroinflammation research. This poster highlights phagocytosis of Aβ1-42, TREM2...

  • Posters

Sygnature Discovery – Automation of iPSC workflows

Discover Axol Bioscience’s iPSC-derived microglia integrated into semi-automated workflows for scalable neuroinflammation research. This poster highlights automation platforms, liquid handling,...

  • Posters

Huntington’s Disease iPSCs-derived striatal neurons with 140 CAG repeats over a 100 day-culture

Explore Axol Bioscience’s iPSC-derived striatal neurons from Huntington’s disease patients with >140 CAG repeats. This poster highlights long-term culture, somatic...

  • Posters

Differential Responses of Chamber-Specific Human iPSC-Derived Cardiomyocytes for In Vitro Cardiotoxicity Studies

Explore Axol Bioscience’s chamber-specific iPSC-derived cardiomyocytes for cardiotoxicity screening. This poster highlights atrial, ventricular, and left ventricular models, metabolic maturation...

  • Posters

iPSC motor neuron NMJ models for enhancing breakthroughs in ALS

Explore Axol Bioscience’s iPSC-derived neuromuscular junction (NMJ) models for ALS research. This poster highlights motor neurons and skeletal muscle cells...

  • Posters

Human iPSC-Derived Cardiomyocytes for High Throughput In Vitro Cardiac Pharmacology and Cardiotoxicity Studies

Explore Axol Bioscience’s ventricular iPSC-derived cardiomyocytes for high-throughput cardiac pharmacology and cardiotoxicity testing. This poster highlights electrophysiological profiling on QPatch...

  • Posters

Establishment of a Quality-Driven Manufacturing Process to Reprogram Human Donor Material into Human Induced Pluripotent Stem Cells (iPSCs) to Support Drug Discovery

Discover Axol Bioscience’s ISO 9001-accredited process for generating high-quality iPSCs from patient and healthy donors. This poster outlines ethical sourcing,...

  • Posters

Differentiation of Multiple iPSC Lines to Different Cell Types to Enable Cohort Analysis in Neurodegeneration: Challenges and Learnings

Explore Axol Bioscience’s cohort-level iPSC differentiation strategy for neurodegeneration research. This poster highlights the generation of astrocytes, cortical excitatory neurons,...

  • Posters

Creation of RUES2 Cell Lines Carrying Targeted Modifications at the HTT Gene

Explore Axol Bioscience’s CRISPR-engineered RUES2 hESC lines with targeted HTT gene modifications for Huntington’s disease research. This poster highlights CAG...

  • Posters

Characterization of Striatal Neurons Derived from >140 CAG iPSCs for Huntington’s Disease Modeling

Explore Axol Bioscience’s iPSC-derived striatal neurons from a Huntington’s disease patient with >140 CAG repeats. This poster highlights somatic instability,...

  • Posters

The Multiplatform Utility of Human iPSC-Derived Neuronal Models to Provide Complex Biological In Vitro Systems for Drug Discovery

Explore Axol Bioscience’s human iPSC-derived neuronal models across 2D and 3D microphysiological systems (MPS). This poster highlights motor and sensory...

  • Posters

innoVitro – Contractility-Based Pharmacological Characterization of hiPSC-Derived Atrial and Ventricular Cardiomyocytes for Preclinical Toxicity Testing

Explore Axol Bioscience’s chamber-specific iPSC-derived cardiomyocytes for contractility-based drug screening. This poster highlights FLEXcyte 96 technology, beat shape analysis, and...

  • Posters

Evaluation of a New Media Designed to Drive Improved Maturity of iPSC-Derived Cardiomyocytes for Cardiac Disease, Cardiotoxicity and Drug Screening

Explore Axol Bioscience’s cardiac maturation media for enhancing the functional maturity of iPSC-derived cardiomyocytes. This poster highlights improvements in sarcomere...

  • Posters

Harnessing the Potential of Induced Pluripotent Stem Cells to Accelerate Drug Discovery for Age-Related Macular Degeneration

Explore Axol Bioscience’s iPSC-derived RPE model for dry AMD research. This poster highlights A2E and blue light-induced stress, genetic risk...

  • Posters

Characterization of Human iPSC-Derived Motor Neuron Disease Model for ALS Drug Discovery

Explore Axol Bioscience’s iPSC-derived motor neuron model for ALS drug discovery. This poster highlights hyperexcitability, loss of synchronous firing, and...

  • Posters

Functional and Pharmacological Differences Between the Contractility of axoCells™ iPSC-Derived Atrial and Ventricular Cardiomyocytes Assessed on the FLEXcyte 96

Explore Axol Bioscience’s chamber-specific iPSC-derived cardiomyocytes for contractility-based drug screening. This poster highlights beat rate, waveform shape, and pharmacological responses...

  • Posters

Cross-Platform Validation of axoCells™ hiPSC-Derived Cardiomyocytes as a Better Human Model for Preclinical Cardiotoxicity Studies

Explore Axol Bioscience’s ventricular iPSC-derived cardiomyocytes validated across MEA, FLEXcyte 96, and CellOPTIQ platforms. This poster highlights chamber-specific pharmacology, marker...

  • Posters

Building a Functionally Relevant In Vitro Model of Alzheimer’s Disease with Patient-Derived iPSCs

Explore Axol Bioscience’s iPSC-derived Alzheimer’s disease model using patient lines with APOE4 and PSEN1 mutations. This poster highlights differentiation into...

  • Posters

Characterization of axoCells™ iPSC-Derived Cortical Inhibitory Interneurons

Explore Axol Bioscience’s iPSC-derived cortical inhibitory interneurons for neuroscience research. This poster highlights marker expression, electrophysiological profiling, and co-culture functionality...

  • Posters

Validation of a Cortical Tri-Culture Model for In Vitro Compound Screening: A Blinded Compound Study

Explore Axol Bioscience’s tri-culture model of cortical neurons, interneurons, and astrocytes for neurotoxicity and drug screening. This poster highlights MEA-based...

  • Posters

Utilizing Flow Cytometry Within a Quality Control Process for an iPSC-Based Manufacturing Facility

Explore Axol Bioscience’s use of flow cytometry for quality control in iPSC-based manufacturing. This poster highlights marker-based pass/fail thresholds for...

  • Posters

Establishing a Robust Platform for Investigating the Pro- and Anti-Inflammatory Response of iPSC-Derived Microglia in Drug Discovery

Explore Axol Bioscience’s iPSC-derived microglia platform for neuroinflammation research and drug screening. This study demonstrates reproducible cytokine release, transcriptomic and...

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